Valencia, Sevilla and Real Betis are all top of their respective groups in the Europa League after four matches.
Valencia beat FC St Gallen 2-3, Piatti scoring twice and Canales getting the third. Besle and Karanovic replied for the Swiss team.
Sevilla were held to a 1-1 draw by Slovan L1berec, with Perotti putting the home side ahead in the first half before Pavelka equalised after the break.
Real Betis were 01 victors over Vitória Guimarães, Vázquez Florido the scorer of the only goal.