Messi and Neymar returned to the fold to help Barcelona overcome Elche 5-0 in the Copa del Rey.
Neymar bagged a pair and Messi, from the penalty spot, Suarez and Alba added three more as Barca eased to victory.
In the other last-16 first leg match played on Thursday, Sevilla were 1-2 winners at Granada. Deulofeu and Gameiro were the scorers for Sevilla, Lass getting an injury time goal for the home side.